TABLE 1.

List of the lncRNAs Significantly Regulated at the 16 h Time Point across Different Doses Compared to Sham-Irradiated Controls

lncRNA	P value AoV	0 Gy		1 Gy			2 Gy			4 Gy			8 Gy			12 Gy
		Meana	SDb	Meana	SDb	P	Meana	SDb	P	Meana	SDb	P	Meana	SDb	P	Meana	SDb	P
1110038B12Rik	0.044	0.542	0.182	0.341	0.023	0.344	0.390	0.048	0.583	0.257	0.146	0.111	0.406	0.252	0.675	0.102	0.049	0.011
1700020I14Rik	0.024	5.228	0.507	5.944	2.729	0.998	12.661	2.632	0.028	7.470	2.909	0.792	4.006	4.616	0.975	4.167	1.890	0.986
1810053B23Rik	0.025	0.017	0.014	0.013	0.017	0.996	0.052	0.029	0.073	0.015	0.011	1.000	0.004	0.006	0.765	0.002	0.001	0.661
AI504432	0.002	0.269	0.177	0.349	0.292	0.997	1.464	0.300	0.002	0.507	0.334	0.798	0.303	0.456	1.000	0.250	0.158	1.000
C130071C03Rik	0.004	0.001	0.000	0.001	0.000	0.726	0.001	0.000	0.054	0.002	0.000	0.001	0.001	0.000	0.034	0.001	0.000	0.125
Crnde	0.017	0.007	0.002	0.020	0.002	0.598	0.046	0.003	0.009	0.044	0.023	0.014	0.027	0.019	0.237	0.023	0.003	0.402
Ftx	0.001	0.007	0.007	0.005	0.008	0.993	0.031	0.010	0.002	0.004	0.003	0.950	0.002	0.001	0.660	0.001	0.000	0.635
Gas5	0.005	2.284	1.337	4.794	0.752	0.198	4.755	1.774	0.208	7.515	1.078	0.004	6.251	1.410	0.025	8.062	2.094	0.002
Gm14005	0.007	1.022	0.240	2.656	1.787	0.385	5.591	0.367	0.003	3.666	1.091	0.078	1.873	2.098	0.860	1.600	0.194	0.964
Gm15832	0.004	0.126	0.026	0.239	0.103	0.815	0.396	0.233	0.157	0.263	0.088	0.694	0.576	0.202	0.012	0.701	0.136	0.002
Malat1	0.03	40.931	12.166	32.029	11.536	0.998	39.792	9.247	1.000	30.557	14.837	0.996	133.120	83.912	0.032	38.508	10.196	1.000
Miat	0.004	0.001	0.000	0.001	0.000	0.730	0.001	0.000	0.040	0.002	0.000	0.001	0.001	0.000	0.035	0.001	0.000	0.128
Neat1	0.027	1.612	0.170	1.705	0.880	1.000	2.201	0.708	1.000	1.608	0.686	1.000	14.078	10.704	0.018	2.506	0.680	0.999
Pvt1	0.002	6.017	1.906	9.970	1.290	0.202	14.031	2.287	0.005	17.271	1.463	0.000	12.102	4.017	0.030	11.630	1.980	0.046
Rab10os	0.053	0.176	0.036	0.151	0.004	0.915	0.158	0.053	0.974	0.130	0.051	0.547	0.172	0.058	1.000	0.062	0.020	0.024
Snhg8	0.015	0.213	0.061	0.152	0.037	0.462	0.131	0.062	0.226	0.084	0.066	0.031	0.081	0.039	0.028	0.041	0.002	0.005
Tmevpg1	0.033	0.018	0.008	0.012	0.008	0.586	0.002	0.001	0.030	0.008	0.010	0.191	0.002	0.000	0.025	0.002	0.001	0.028

Notes. Mouse lncFinder arrays were utilized to profile the status of 84 characterized lncRNAs at different radiation doses (1, 2, 4, 8 and 12 Gy). RNA was isolated 16 h postirradiation, converted to cDNA, and PCR assays were performed according to the manufacturer’s protocol. Statistical significance was calculated using ANOVA along with Dunnett’s test to compute P values.

^aMean = average relative expression compared to endogenous control [Gt(ROSA)26Sor].

^bSD = standard deviation in irradiated vs. sham-irradiated samples.