TABLE 2.

List of the lncRNAs Significantly Regulated at the 24 h Time Point across Different Doses Compared to Sham-Irradiated Controls

lncRNA	P value AoV	0 Gy		1 Gy			2 Gy			4 Gy			8 Gy			12 Gy
		Meana	SDb	Meana	SDb	P	Meana	SDb	P	Meana	SDb	P	Meana	SDb	P	Meana	SDb	P
1700020I14Rik	0.01	2.675	0.682	3.800	0.802	1.000	15.832	10.331	0.103	19.181	6.911	0.034	12.504	4.794	0.282	24.040	8.644	0.007
1810053B23Rik	0.025	0.004	0.002	0.010	0.007	1.000	0.152	0.116	0.349	0.305	0.181	0.019	0.219	0.121	0.106	0.214	0.085	0.116
AI504432	0.01	0.102	0.033	0.229	0.102	1.000	3.042	2.645	0.293	3.354	1.223	0.219	1.441	0.453	0.869	6.978	3.822	0.005
Airn	0.028	0.070	0.018	0.079	0.032	0.983	0.071	0.016	1.000	0.044	0.028	0.495	0.018	0.017	0.047	0.033	0.015	0.205
Crnde	0.025	0.007	0.003	0.014	0.006	0.985	0.031	0.020	0.368	0.052	0.021	0.029	0.053	0.010	0.025	0.043	0.027	0.091
Ftx	0.017	0.003	0.001	0.007	0.003	1.000	0.556	0.493	0.039	0.629	0.186	0.019	0.289	0.126	0.416	0.418	0.065	0.143
Gas5	0.002	3.845	0.098	6.947	1.629	0.061	9.618	1.005	0.001	8.427	1.567	0.006	7.192	2.111	0.041	9.560	0.737	0.001
Gm14005	0.003	0.366	0.072	1.409	0.041	0.998	11.350	8.595	0.041	15.744	3.770	0.005	9.354	3.249	0.106	15.536	4.554	0.005
Gm15051	0	0.001	0.000	0.005	0.001	0.986	0.021	0.017	0.143	0.046	0.008	0.001	0.011	0.004	0.673	0.052	0.017	0.000
H19	0.016	0.002	0.002	0.002	0.002	1.000	0.032	0.026	0.175	0.047	0.027	0.028	0.022	0.008	0.478	0.049	0.017	0.021
Jpx	0	0.058	0.003	0.050	0.028	0.891	0.019	0.007	0.007	0.007	0.002	0.001	0.010	0.003	0.001	0.002	0.003	0.000
Kcnq1ot1	0	0.166	0.004	0.153	0.031	0.956	0.119	0.047	0.157	0.035	0.012	0.000	0.026	0.022	0.000	0.018	0.014	0.000
Pvt1	0.003	3.982	0.596	7.793	1.632	0.690	13.114	3.533	0.069	16.004	4.856	0.015	21.608	7.787	0.001	13.951	1.466	0.045
Rab10os	0.054	0.152	0.027	0.186	0.027	0.346	0.179	0.019	0.540	0.187	0.015	0.318	0.125	0.022	0.565	0.153	0.033	1.000
Snhg1	0.014	0.144	0.044	0.166	0.077	0.947	0.099	0.038	0.536	0.066	0.003	0.124	0.051	0.008	0.057	0.046	0.017	0.044
Snhg8	0.003	0.196	0.056	0.235	0.079	0.769	0.153	0.029	0.694	0.074	0.037	0.031	0.065	0.021	0.020	0.089	0.034	0.060
Tmevpg1	0.001	0.028	0.012	0.014	0.006	0.074	0.008	0.007	0.008	0.001	0.001	0.001	0.001	0.001	0.001	0.001	0.001	0.001

Notes. Mouse lncFinder arrays were utilized to profile the status of 84 characterized lncRNAs at different radiation doses (1, 2, 4, 8 and 12 Gy). RNA was isolated 24 h postirradiation, converted to cDNA, and PCR assays were performed according to the manufacturer’s protocol. Statistical significance was calculated using ANOVA along with Dunnett’s test to compute P values.

^aMean = average relative expression compared to endogenous control [Gt(ROSA)26Sor].

^bSD = standard deviation in irradiated vs. sham-irradiated samples.