TABLE 3.

List of the lncRNAs Significantly Regulated at the 48 h Time Point across Different Doses Compared to Sham-Irradiated Controls

lncRNA	P value AoV	0Gy		1 Gy			2 Gy			4 Gy			8 Gy			12 Gy
		Meana	SDb	Meana	SDb	P	Meana	SDb	P	Meana	SDb	P	Meana	SDb	P	Meana	SDb	P
1700020I14Rik	0.007	10.976	4.295	10.462	2.859	1.000	29.318	3.624	0.021	30.273	3.121	0.015	27.433	11.723	0.039	19.843	8.714	0.381
1810053B23Rik	0.041	0.156	0.094	0.108	0.045	0.614	0.168	0.028	0.998	0.104	0.008	0.550	0.069	0.027	0.143	0.040	0.026	0.039
AI504432	0.007	0.891	0.261	2.095	0.643	0.990	8.338	1.033	0.078	11.980	2.114	0.008	10.920	3.340	0.015	9.919	7.349	0.029
Airn	0.022	0.161	0.033	0.237	0.166	0.998	0.177	0.027	1.000	0.194	0.007	1.000	0.228	0.188	0.999	1.049	0.686	0.014
Firre	0.055	0.319	0.104	0.277	0.328	1.000	0.099	0.063	0.700	0.185	0.072	0.933	0.230	0.173	0.987	0.783	0.438	0.128
Gas5	0.005	2.913	0.995	3.332	0.556	0.998	7.351	1.142	0.026	9.076	2.705	0.003	6.009	2.296	0.144	5.902	1.172	0.164
Gm14005	0.019	3.307	1.358	6.299	5.282	0.982	23.191	6.985	0.026	23.356	9.173	0.025	20.808	12.497	0.053	11.737	3.903	0.529
Gm15051	0	0.011	0.001	0.016	0.012	0.986	0.044	0.005	0.060	0.067	0.008	0.002	0.069	0.011	0.001	0.088	0.030	0.000
Gm15832	0.002	0.184	0.051	0.243	0.111	0.879	0.157	0.052	0.994	0.520	0.160	0.003	0.139	0.052	0.955	0.301	0.047	0.403
Malat1	0.047	126.011	76.639	103.769	115.408	0.998	32.877	6.965	0.590	71.807	40.252	0.908	64.633	51.955	0.861	288.616	153.626	0.153
Meg3	0.002	0.081	0.070	0.119	0.089	1.000	0.048	0.034	1.000	0.091	0.018	1.000	0.275	0.236	0.912	1.381	0.744	0.002
Pvt1	0.05	3.802	1.556	5.026	1.518	0.648	7.188	0.778	0.024	4.543	0.097	0.917	3.758	1.583	1.000	4.346	1.246	0.974
Snhg8	0.027	0.348	0.012	0.450	0.139	0.531	0.272	0.073	0.758	0.315	0.051	0.987	0.159	0.078	0.091	0.220	0.127	0.339
Tmevpg1	0	0.031	0.016	0.068	0.018	0.005	0.012	0.006	0.170	0.012	0.007	0.196	0.002	0.001	0.025	0.003	0.001	0.035
Tug1	0.026	3.939	2.013	3.614	1.706	0.998	4.774	0.649	0.882	6.634	1.021	0.084	4.357	1.040	0.992	7.056	0.423	0.042

Notes. Mouse lncFinder arrays were utilized to profile the status of 84 characterized lncRNAs at different radiation doses (1, 2, 4, 8 and 12 Gy). RNA was isolated 48 h postirradiation, converted to cDNA, and PCR assays were performed according to the manufacturer’s protocol. Statistical significance was calculated using ANOVA along with Dunnett’s test to compute P values.

^aMean = average relative expression compared to endogenous control [Gt(ROSA)26Sor].

^bSD = standard deviation in irradiated vs. sham-irradiated samples.