. Author manuscript; available in PMC: 2018 May 24.

Published in final edited form as: J Drug Deliv Sci Technol. 2017 Nov 21;43:453–460. doi: 10.1016/j.jddst.2017.11.013

Table 1.

Characterization of mNP used for intranasal delivery of different nucleic acid payloads to the brain.

Payloads	Molecular ratios of mNP constituents			Average Diameter ± Standard Error, nm^a
Payloads	Nucleic acid	Mn chelate	Chitosan	Average Diameter ± Standard Error, nm^a
Stealth anti-GFP siRNA	2–2.3	12–14	1	122 ± 15
mCherry RFP plasmid	1	321–365	25–30	140 ± 18
Cy-3-hsiRNA	2–2.5	11–13	1	125 ± 14

Number of replications n = 6.