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. Author manuscript; available in PMC: 2018 May 24.
Published in final edited form as: J Med Chem. 2017 Feb 9;60(4):1580–1590. doi: 10.1021/acs.jmedchem.6b01852

Figure 1.

Figure 1

AM2-S31N inhibitors. (A) Pharmacophore of AM2-S31N inhibitors. (B) Representative isoxazole-containing AM2-S31N inhibitor. (C) Synthesis of potent AM2-S31N inhibitors by microwave-assisted Suzuki–Miyaura cross-coupling.