Table 4.
Physiological activity patterns of all recorded medial septal neurons during hippocampal theta oscillations and SWR events
| Neuron | Mean theta phase of firing (deg.) | Mean theta vector length of firing (r)* | Mean firing rate, non-theta freq. (Hz) | Mean firing rate, theta freq. (Hz) | Mean number of spikes per theta cycle (SD) | Theta cycle count | Mean firing rate during SWRs (Hz) | Mean firing rate, of surrogate SWRs (Hz) | SWR index** | (p), SWR firing rate comparison: Kolmogorov–Smirnov test | SWR count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SWR-unchanged neurons | |||||||||||
| D55c | 150.80 | 0.63850 | 8.67 | 11.70 | 2.8 (0.7) | 715 | 4.70 | 3.19 | 0.19 | 0.627586 | 68 |
| M40b | 294.20 | 0.61700 | 37.34 | 37.00 | 9.5 (2.3) | 1140 | 34.97 | 37.41 | − 0.03 | 0.434968 | 53 |
| M40g | 38.80 | 0.59031 | 7.11 | 13.10 | 3.7 (2.1) | 213 | 6.03 | 6.26 | − 0.02 | 0.371590 | 49 |
| M66b | 275.99 | 0.33157 | 8.12 | 8.40 | 3 (1.8) | 2129 | 8.38 | 8.08 | 0.02 | 0.909448 | 20 |
| M80b | 112.69 | 0.49001 | 10.59 | 23.80 | 5.9 (3.8) | 1691 | 7.82 | 8.25 | − 0.03 | 0.986206 | 94 |
| M82b | 283.23 | 0.66308 | 15.89 | 9.10 | 2.4 (1) | 1294 | 14.14 | 16.76 | − 0.08 | 0.955708 | 35 |
| SWR-suppressed neurons | |||||||||||
| M21c | 270.56 | 0.39783 | 19.40 | 19.80 | 4.9 (1.6) | 881 | 1.91 | 19.68 | − 0.82 | 0.000016 | 14 |
| M22c | 288.50 | 0.81819 | 16.96 | 17.42 | 3.9 (1.1) | 355 | 3.90 | 16.91 | − 0.63 | 0.002220 | 18 |
| M30e | 305.60 | 0.36712 | 18.22 | 19.40 | 4.7 (1.7) | 2361 | 3.79 | 19.03 | − 0.67 | < 0.00001 | 25 |
| M31g | 267.38 | 0.61670 | 9.22 | 11.69 | 3.3 (2.1) | 78 | 0.00 | 9.36 | − 1.00 | 0.010166 | 15 |
| M37b | 96.80 | 0.56896 | 8.51 | 13.70 | 4.1 (1.4) | 124 | 1.12 | 9.06 | − 0.78 | 0.042998 | 20 |
| M37e | 64.61 | 0.70234 | 10.93 | 14.80 | 4.7 (2.1) | 463 | 2.62 | 10.92 | − 0.61 | 0.042038 | 44 |
| M37f | 330.31 | 0.52629 | 11.86 | 11.00 | 3.4 (2.1) | 325 | 2.27 | 11.56 | − 0.67 | 0.000080 | 30 |
| M37h | 171.96 | 0.37500 | 35.69 | 55.50 | 15.3 (7.2) | 497 | 15.87 | 37.79 | − 0.41 | 0.000044 | 57 |
| M41e | 220.73 | 0.67442 | 24.12 | 25.60 | 7.1 (3.6) | 1046 | 0.24 | 23.94 | − 0.98 | < 0.00001 | 52 |
| M60a | 262.50 | 0.72908 | 4.35 | 5.00 | 1.7 (0.9) | 628 | 0.79 | 4.35 | − 0.69 | 0.035504 | 43 |
| M74b | 224.48 | 0.68309 | 33.09 | 20.70 | 5.3 (1.4) | 1163 | 21.70 | 34.21 | − 0.22 | 0.000668 | 17 |
| M76a | 264.82 | 0.49227 | 23.86 | 20.90 | 5 (2.8) | 2547 | 4.48 | 24.13 | − 0.69 | < 0.00001 | 35 |
| M77b | 267.22 | 0.17907 | 15.92 | 42.50 | 10 (2.3) | 386 | 2.01 | 15.88 | − 0.77 | < 0.00001 | 116 |
| M77c | 295.96 | 0.73012 | 20.36 | 26.10 | 5.6 (1.8) | 5368 | 3.03 | 19.18 | − 0.73 | < 0.00001 | 57 |
| M78a | 310.00 | 0.72527 | 19.83 | 18.50 | 4.4 (2.1) | 706 | 15.39 | 19.57 | − 0.12 | 0.036443 | 71 |
| M82a | 327.48 | 0.58180 | 12.49 | 7.94 | 2.3 (1.2) | 1524 | 1.22 | 13.22 | − 0.83 | < 0.00001 | 35 |
| M82e | 178.90 | 0.21709 | 43.33 | 44.80 | 11.3 (5.5) | 128 | 3.78 | 46.02 | − 0.85 | < 0.00001 | 21 |
| SWR-active neurons | |||||||||||
| M31b | 38.55 | 0.43392 | 10.05 | 11.40 | 3.3 (2.2) | 1443 | 34.07 | 8.29 | 0.61 | < 0.00001 | 46 |
| M31h | 303.53 | 0.52617 | 41.72 | 46.09 | 12.4 (5) | 306 | 67.72 | 40.59 | 0.25 | < 0.00001 | 46 |
| M40d | 33.20 | 0.51999 | 4.63 | 8.60 | 2.2 (1.1) | 425 | 11.79 | 3.98 | 0.50 | 0.004131 | 12 |
| M40f | 16.20 | 0.63768 | 16.98 | 20.00 | 5.2 (3.2) | 789 | 43.89 | 22.06 | 0.33 | < 0.00001 | 57 |
| M41d | 70.96 | 0.46451 | 16.58 | 31.80 | 7.9 (4.2) | 44 | 30.56 | 14.93 | 0.34 | 0.010170 | 22 |
| M60d | 207.28 | 0.64577 | 9.61 | 15.07 | 3.8 (1.1) | 578 | 13.74 | 9.62 | 0.18 | 0.011395 | 47 |
| M65b | 56.19 | 0.66666 | 8.84 | 11.70 | 2.7 (1.3) | 1543 | 14.44 | 8.81 | 0.24 | 0.000333 | 30 |
| M67a | 39.39 | 0.64298 | 8.43 | 12.60 | 3.2 (1.3) | 489 | 11.86 | 8.84 | 0.15 | 0.002674 | 25 |
| M74c | 318.30 | 0.75708 | 14.27 | 28.90 | 7.3 (4.1) | 1241 | 30.56 | 12.65 | 0.41 | 0.000029 | 42 |
| M75a | 144.06 | 0.58351 | 5.45 | 12.80 | 3.5 (0.9) | 578 | 7.57 | 5.48 | 0.16 | 0.005440 | 41 |
| M77a | 269.93 | 0.73417 | 16.25 | 49.90 | 10 (3.6) | 3252 | 39.62 | 16.31 | 0.42 | 0.000055 | 41 |
| M79a | 14.78 | 0.68242 | 10.35 | 24.05 | 5.4 (2) | 1547 | 17.39 | 8.19 | 0.36 | < 0.00001 | 57 |
| M80d | 129.93 | 0.67793 | 8.11 | 13.40 | 3.5 (1.2) | 71 | 27.73 | 7.84 | 0.56 | < 0.00001 | 67 |
| M82f | 49.82 | 0.54672 | 10.69 | 23.05 | 6 (3.1) | 919 | 23.42 | 9.64 | 0.42 | < 0.00001 | 27 |
Bold, juxtacellularly labeled neurons
*Values of r between 0 and 1, maximally correlated = 1
**See “Materials and methods”