Table 1.
SNP | OR (AgP) | OR (CHD) | P (AgP) | P (CHD) | CI 95% (AgP) | CI 95% (CHD) | N (AgP) | N (CHD) |
rs2891168 | 1.44 | 1.42 | 4.4 E-3 | 1.1 E-6 | 1.12–1.86 | 1.23–1.64 | 159/736 | 1,104/736 |
rs1333042 | 1.44 | 1.42 | 4.8 E-3 | 1.2 E-6 | 1.12–1.85 | 1.23–1.64 | ||
rs1333048 | 1.48 | 1.39 | 2.5 E-3 | 7.6 E-6 | 1.15–1.92 | 1.20–1.60 |
Association statistics of tree haplotype tagging SNPs at the relevant chromosome 9p21.3 risk region, multiplicative model adjusted for smoking, diabetes, and gender in a logistic regression model. AgP: aggressive periodontitis (generalized), CHD, coronary heart disease (disease onset <55 years), OR: odds ratio, CI: confidence interval, P: P-value obtained from a Wald test, N: number of cases/controls. Data extracted from ref. (17).