Figure 1. A chart demonstrating the study subjects in groups that had serum, liver and bile measurements of plant sterols and liver mRNA expression available.

Of the original cohort of 150 subjects that had serum plant sterol measurements available, a distinct liver phenotype could be recognized in 138 subjects [normal liver (normal, n=44) and nonalcoholic fatty liver disease (NAFLD, n=94)]. Of those in NAFLD group, 28 had simple steatosis and 27 had nonalcoholic steatohepatitis (NASH). Of the 138 subjects who had serum plant sterol measurements, liver (n=38) and bile (n=41) sterol measurements, and liver mRNA expression (n=102) were performed. Liver and bile sterol measurements were from different subjects.