Table 4. The content of Hyp (μg/ml), IL-6 (pg/ml), and TGF-β (pg/ml) in serum in each group (mean ± SD).
| Group | 3rd day | 7th day | 11th day | 15th day | |
|---|---|---|---|---|---|
| Hyp | EE | 19.23 ± 1.03 | 22.01 ± 1.36 | 27.24 ± 1.87†‡ | 26.64 ± 2.25†‡ |
| JWH | 18.89 ± 1.27 | 21.76 ± 2.24 | 25.32 ± 2.12† | 24.82 ± 2.18* | |
| Control | 18.35 ± 1.19 | 21.34 ± 1.24 | 21.86 ± 2.49 | 22.67 ± 3.16 | |
| IL-6 | EE | 253.71 ± 30.48†§ | 456.37 ± 26.33†§ | 193.67 ± 15.58† | 62.36 ± 16.36 |
| JWH | 164.33 ± 7.38* | 225.54 ± 18.96† | 201.35 ± 5.33† | 67.83 ± 5.35 | |
| Control | 135.60 ± 14.37 | 161.34 ± 22.56 | 150.34 ± 8.39 | 63.41 ± 3.98 | |
| TGF-β | EE | 215.33 ± 17.88† | 208.02 ± 21.45†‡ | 191.63 ± 14.76†‡ | 138.24 ± 6.35 |
| JWH | 203.11 ± 34.72* | 187.04 ± 19.61† | 166.24 ± 11.72* | 136.23 ± 3.45 | |
| Control | 168.07 ± 9.82 | 150.76 ± 6.39 | 141.13 ± 10.33 | 135.77 ± 4.65 |
Abbreviations: Hyp, hydroxyproline; TGF-β, transforming growth factor-β; *P<0.05 compared with the control group; †P<0.01 compared with the control group; ‡P<0.05 compared with the JWH group; §P<0.01 compared with the JWH group.