Table 1.
Characteristics of exposed MERS case | Status of subjects when they were exposed to MERS1 |
Selection or response rate (%)2 | |||||||
---|---|---|---|---|---|---|---|---|---|
Patient | Family | Visitor | Healthcare worker | Colleague | Unknown | Total | |||
Quarantined subjects | Spreaders with 5 or more cases | 1,141 | 71 | 417 | 558 | 3 | 657 | 2,847 | |
Spreaders with 1 to 4 cases | 1,067 | 64 | 364 | 198 | 35 | 375 | 2,103 | ||
Non-spreaders | 3,489 | 321 | 1,613 | 1,260 | 453 | 2,745 | 9,881 | ||
Total | 5,697 | 456 | 2,394 | 2,016 | 491 | 3,777 | 14,831 | ||
Selected subjects | Spreaders with 5 or more cases | 744 | 60 | 254 | 115 | 3 | 212 | 1,388 | 48.8 |
Spreaders with 1 to 4 cases | 191 | 10 | 105 | 10 | 0 | 29 | 345 | 16.4 | |
Non-spreaders | 626 | 101 | 281 | 184 | 101 | 265 | 1,558 | 15.8 | |
Total | 1,561 | 171 | 640 | 309 | 104 | 506 | 3,291 | 22.2 | |
Selection rate (%) | 27.4 | 37.5 | 26.7 | 15.3 | 21.2 | 13.4 | 22.2 | ||
Study participants | Spreaders with 5 or more cases | 252 | 53 | 152 | 94 | 1 | 0 | 552 | 39.8 |
Spreaders with 1 to 4 cases | 60 | 4 | 62 | 12 | 0 | 1 | 139 | 40.3 | |
Non-spreaders | 262 | 109 | 271 | 201 | 50 | 26 | 919 | 59.0 | |
Total | 574 | 166 | 485 | 307 | 51 | 27 | 1,610 | 48.9 | |
Response rate (%) | 36.8 | 97.1 | 75.8 | 99.4 | 49.0 | 5.3 | 48.9 | ||
Subjects with seropositive ELISA (IFA/PRNT) | Spreaders with 5 or more cases | 2 (1) | 1 (0) | 3 (1) | |||||
Spreaders with 1 to 4 cases | 1 (0) | 1 (0) | |||||||
Non-spreaders | 3 (0) | 3 (0) | |||||||
Total | 6 (1) | 1 (0) | 7 (1) | ||||||
Seropositive rate (%) | 1.05 (0.17) | 0.33 (–) | 0.43 (0.06) |
MERS, Middle East Respiratory Syndrome; ELISA, enzyme-linked immunospecific assay; IFA, immunofluorescence assay; PRNT, plaque reduction neutralization antibody test.
Inpatients or outpatients at a MERS-affected hospital, family of people living with or a paid caregiver of the MERS case, visitors of the hospitalized MERS case, healthcare workers employed at a MERS-affected hospital, and colleagues of co-workers of a MERS case.
Selection rates varied by characteristics of the MERS case subjects were exposed to (i.e. transmission intensity) and the subjects’ status (i.e. exposure intensity).