Table 1.
Baseline | 6 months | 12 months | 18 months | 24 months | 30 months | 36 months | 42 months | 48 months | p value | |
---|---|---|---|---|---|---|---|---|---|---|
MMSE ADAS-Cog |
18.9±5.4 21.5±8.4 |
18.4±4.7 22.6±8.2 |
19.2±5.0 20±8.3 |
19.1±5.3 20.8±8.5 |
18.9±5.2 21.5±8.4 |
18.3±5.5 22.5±8.8 |
17.2±5.4 24.6±9.3 |
16.8±5.1 25.3±10.3 |
16.3±4.8 27.7±12.8 |
<0.001 <0.001 |
Values are means ± standard deviations. MMSE, Mini-Mental State Examination; ADAS-Cog, Alzheimer's Disease Assessment Scale-Cognitive Subscale.