Table 2.
Mean lipid concentrations before and after intervention in all groups
| Control (n = 37) |
R10 (n = 20) |
R20 (n = 15) |
A10 (n = 16) |
A20 (n = 18) |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| baseline | at 6 months | baseline | at 6 months | baseline | at 6 months | baseline | at 6 months | baseline | at 6 months | |
| TC | 230.5±18.7 | 208.8±19.3** | 259.8±33.3 | 185.0±33.3** | 302.7±52.3 | 214.6±44.1** | 260.4±23.2 | 186.5±22.7** | 277.4±42.1 | 205.3±27.6** |
| LDL-c | 152.9±12.6 | 135.7±13.4** | 176.6±25.3 | 105.5±25.8** | 214.8±50.9 | 134.0±48.8** | 180.1±19.3 | 113.9±24.7** | 191.2±31.5 | 129.1±27.2** |
| HDL-c | 47.1±9.4 | 47.6±9.1* | 49.6±12.4 | 53.8±12.5** | 50.8±17.2 | 54.2±21.0** | 43.4±5.7 | 47.9±7.9** | 45.3±11.7 | 47.3±11.7** |
| TG | 152.5±65.9 | 127.7±52.8** | 167.9±49.6 | 128.7±41.5** | 185.0±109.6 | 131.8±54.4** | 184.2±80.3 | 123.1±35.2** | 204.3±108.3 | 144.3±61.7** |
| TSH | 1.59±0.91 | 1.55±0.74* | 1.96±0.97 | 1.72±0.79* | 1.23±0.82 | 1.33±0.73* | 1.96±0.89 | 1.98±0.85* | 2.04±0.92 | 1.86±0.95* |
Values are expressed as means ± SD. R10, rosuvastatin 10 mg; R20, rosuvastatin 20 mg; A10, atorvastatin 10 mg; A20, atorvastatin 20 mg; TC, total cholesterol; LDL-c, low-density lipoprotein cholesterol; HDL-c, high density lipoprotein cholesterol; TG, triglycerides; TSH, thyrotropin-stimulating hormone.
*
p < 0.05;
**
p < 0.05.