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Table 1. Baseline characteristics.

Total No LVH LVH p value
N, % 281 103 (36.6) 178 (63.3)
Male 143 (51) 42 (40.5) 101 (56.7) < 0.001
Age, year 63 ± 12 61 ± 11 66 ± 12 0.02
BMI, kg/m2 25.3 ± 3.68 25.3 ± 3.78 25.2 ± 3.60 0.214
Hemodialysis duration, years 5.7 ± 3.3 3.8 ± 4.1 8.2 ± 3.5 0.012
Systolic BP, mmHg 142 ± 14 138 ± 11 153 ± 16 0.034
Diastolic BP, mmHg 78 ± 9 77 ± 11 79 ± 8 0.751
Hypertension 243 (86.7) 77 (74.7) 166 (93.2) < 0.001
Diabetes 169 (60.2) 63 (61.1) 106 (59.5) 0.391
CAD 109 (38.8) 30 (29.1) 79 (44.4) 0.015
History of HF hospitalization 94 (33.3) 19 (18.4) 75 (42.1) < 0.001
History of CVA 34 (12.2) 9 (8.7) 25 (14.4) 0.478
Medications
 Anti-platelets 132 (46.9) 44 (43.1) 88 (49.4) 0.392
 Aldactone 89 (31.6) 20 (19.4) 79 (44.3) 0.004
 ACEIs/ARBs 92 (32.7) 33 (32.5) 59 (33.1) 0.124
 Beta-blockers 52 (18.5) 15 (14.5) 37 (20.8) 0.218
 CCBs 100 (35.5) 27 (26.2) 73 (41.0) 0.032
 Statins 20 (7.1) 6 (5.8) 14 (7.9) 0.184
Laboratory parameters
 Hemoglobin, g/dl 10.93 ± 1.5 10.90 ± 1.72 10.97 ± 1.17 0.482
 HbA1c, % 7.50 ± 1.89 7.43 ± 2.27 7.58 ± 1.45 0.651
 Albumin, g/dl 3.97 ± 0.33 4.00 ± 0.32 3.92 ± 0.35 0.194
 Parathyroid hormone, pg/ml 379.27 ± 191.2 365.95 ± 183.71 394.38 ± 196.50 0.221
 C-reactive protein, md/dl 14.6 ± 24.9 15.4 ± 29.3 12.9 ± 19.3 0.186
 ADMA (μmol/L) 1.08 ± 0.17 0.87 ± 0.17 1.26 ± 0.16 0.014
 Urea reduction ratio, % 75 ± 6.6 74 ± 5.3 75 ± 7.9 0.229
Echocardiographic parameters
 LVDD, mm 44.9 ± 6.68 40.2 ± 5.58 47.7 ± 5.64* < 0.001
 LVESD, mm 29.0 ± 6.10 24.8 ± 4.30 31.5 ± 5.68* < 0.001
 IVS, mm 12.6 ± 2.91 11.6 ± 1.42 13.2 ± 3.37* < 0.001
 PWd, mm 12.0 ± 2.54 11.2 ± 1.55 12.5 ± 2.88* 0.021
 LA, mm 39.2 ± 6.26 36.0 ± 6.54 41.1 ± 5.32* < 0.001
 LVEF, % 63 ± 10 64 ± 8 62 ± 10 0.228
 TRPG, mmHg 28 ± 12.2 21 ± 9.7 41 ± 12.2 0.017
 E/A ratio 0.86 ± 0.25 0.81 ± 0.17 0.89 ± 0.28 0.712
 LVMI, g/m2 127 ± 49.6 87 ± 15.9 148 ± 48.3 < 0.001
 Advanced diastolic dysfunction, % 124 (44.1) 27 (26.2) 97 (54.5) 0.002

ACEIs, angiotensin-converting enzyme inhibitors; ADMA, asymmetrical dimethylarginine; ARBs, angiotensin II receptor blocker; BMI, body mass index; BP, blood pressure; CAD, coronary artery disease; CCBs, calcium channel blockers; CVA, cerebral vascular accident; E/A, the ratio of peak velocity flow in early diastole (the E wave) to peak velocity flow in late diastole caused by atrial contraction (the A wave); HbA1c, hemoglobin A1c; IVS, interventricle septum; LA, left atrium dimension; LVEDD, left ventricle end-diastolic dimensions; LVESD, left ventricle end-systolic dimensions; LVMI, left ventricle mass index; PWd, posterior wall thickness; TRPG, tricuspid regurgitation pressure gradient.