Table 1. Baseline characteristics according to tertiles of serum albumin levels.
| Variable | Unit | Total (n = 1,352) |
Serum albumin levels (g/dL) | P for trend | ||
|---|---|---|---|---|---|---|
| Low group ≤3.9 (n = 458) |
Middle group 4.0–4.3 (n = 456) |
High group ≥4.4 (n = 438) |
||||
| Clinical parameters | ||||||
| Age | years | 35 (23–47) | 42 (27–53) | 31 (23–45) | 26 (20–39) | <0.001 |
| Sex (male) | % | 45.3 | 39.7 | 45.0 | 51.4 | <0.001 |
| BMI | kg/m2 | 22 (20–24) | 22 (20–24) | 22 (20–24) | 21 (20–24) | 0.06 |
| SBP | mmHg | 122 (113–138) | 128 (114–144) | 122 (114–134) | 120 (112–132) | <0.001 |
| eGFR | mL/min/1.73 m2 | 78 (58–99) | 62 (45–82) | 82 (63–101) | 89 (71–104) | <0.001 |
| Urinary protein excretion | g/24 h | 0.79 (0.27–1.75) | 1.67 (0.79–3.19) | 0.59 (0.24–1.25) | 0.40 (0.14–0.9) | <0.001 |
| Total cholesterol | mg/dL | 196 (169–227) | 213 (183–249) | 190 (164–217) | 188 (166–216) | <0.001 |
| Triglycerides | mg/dL | 102 (70–151) | 117 (83–171) | 93 (66–145) | 93 (61–142) | <0.001 |
| Pathological parameters | ||||||
| M1 | % | 12.4 | 19.7 | 11.8 | 5.3 | <0.001 |
| E1 | % | 39.9 | 54.6 | 63.2 | 37.2 | 0.01 |
| S1 | % | 76.4 | 83.2 | 74.3 | 71.5 | <0.001 |
| T0 | % | 74.2 | 65.5 | 80.0 | 77.2 | <0.001 |
| T1 | % | 15.8 | 20.3 | 14.0 | 13.0 | |
| T2 | % | 10.0 | 14.2 | 5.9 | 9.8 | |
| C1–2 | % | 34.7 | 39.1 | 32.7 | 32.2 | 0.03 |
Continuous variables are presented as median (interquartile range) and categorical variables as percentages.
Abbreviations: BMI, body mass index; C, crescent score; E, endocapillary hypercellularity score; eGFR, estimated glomerular filtration rate; M, mesangial hypercellularity score; S, segmental glomerulosclerosis score; SBP, systolic blood pressure; T, tubular atrophy/interstitial fibrosis score.