Table 2.
Dietary patterns and Colorectal Cancer Survival (Multivariable adjusted analysis); Newfoundland and Labrador Familial Colorectal Cancer Cohort (1999–2003)
| Dietary Pattern Identified by | Combined Mortality, Recurrence and Metastasis | Overall Mortality | ||
|---|---|---|---|---|
| HRa (95% CI) | P-trend | HR (95% CI) | p-trend | |
| Factor Analysis | ||||
| Processed Meat patterna | 1.82 (1.07–3.09)* | 0.09 | 1.53 (0.85–2.27) | 0.25 |
| Prudent Vegetable Patterna | 1.12 (0.69–1.84) | 0.62 | 1.03 (0.61–1.75) | 0.90 |
| High-sugar Patterna | 1.02 (0.62–1.69) | 0.89 | 1.27 (0.72–2.23) | 0.62 |
| Cluster Analysis | ||||
| Fruit and Veg, Whole Grain, Fish, wine (Cluster I) | 1c | 1c | ||
| Meat, dairy products(Cluster II), | 2.19 (1.03–4.67)* | 2.04 (0.96–4.35) | ||
| Refined grains, sugar soft Drinks (Cluster III) | 1.95 (1.13–3.37)* | 2.05 (1.18–3.57)* | ||
| Many foods (Cluster IV) | 1.55 (0.92–2.61) | 1.50 (0.9–2.56) | ||
| Index Based | ||||
| DIIa | 0.89 (0.56–1.42) | 0.46 | 0.78 (0.47–1.25) | 0.33 |
| Alt. Mediterranean Diet Scoreb | 1.44 (0.92–2.25) | 0.08 | 1.62 (1.04–2.56)* | 0.03 |
| Recommended Food Scoreb | 1.51(0.92–2.48) | 0.06 | 1.54 (0.92–2.56) | 0.045 |
aHazards Ratio while comparing with highest quartile to the lowest (reference quartile)
bHazards Ratio while comparing with lowest quartile to highest (reference quartile)
cReference group
*Statistically significant
HR ratios Adjusted for energy, stage of cancer, sex, age, marital status, tumour location, screening history, intake of alcohol, radiation and chemo therapy status, Microsatellite instability status wherever applicable
Events are defined as all-cause deaths for overall Mortality and death/recurrence/metastasis (which occurred earliest) for cMRM