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. 2018 May 24;10:48. doi: 10.1186/s13195-018-0375-x

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Effect of APOE on axial diffusivity (AxD) (from top to bottom: recessive and additive components). No dominant component was observed. Only contrast maps associated with higher AxD in ε4 carriers showed significant voxels. The white matter skeleton is shown in green. Suprathreshold clusters are presented in colors from dark red to white (1 − p > 0.95, familywise error rate- and threshold-free cluster enhancement-corrected)