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AQP4 knockdown ameliorated GD-induced disruption of in vitro BBB models. a The effects of AQP4 knockdown on in vitro BBB permeability after GD. b The levels of claudin-5 protein in bEnd.3 cells were detected via Western blot. c Quantification of claudin-5 expression. **p < 0.01 vs. the control + 5.5 mM glucose group, #p < 0.05 or ##p < 0.01 vs. the control + 0 mM glucose group. n = 3 in each group
