Table 2. Inhibitory activity of peptides on infection by primary HIV-1 isolates a .
Compound | EC50 (nM) for inhibiting |
||
US4/GS 007 (B, R5) | 93IN101 (C, R5) | 92TH009 (A/E, R5) | |
(N36M)3 | 9.4 ± 1.2 | 5.9 ± 2.0 | 1.5 ± 0.1 |
(N36MEK1)3 | 29.2 ± 11.2 | 20.1 ± 5.6 | 14.5 ± 4.1 |
(N36MEK2)3 | 7.1 ± 2.5 | 5.2 ± 0.9 | 1.5 ± 0.6 |
T20 | 20.4 ± 2.9 | 22.1 ± 0.9 | 19.0 ± 0.5 |
aPeptides were tested in triplicate, and the data are presented as the mean ± standard deviation.