Figure 4.

Rota-Rod test performance in mice in the control (injection of normal saline), monosodium iodoacetate (0.1 mg)-injected and human umbilical cord mesenchymal stem cell-transplanted groups (n = 6, each group). The Rota-Rod test was repeated five times each day on days 0, 7, 14, 28, and 35. The results from days 7, 14, 28, and 35 were then compared with the mean duration on day 0 in each mouse. The human umbilical cord mesenchymal stem cell-transplanted mice showed significantly different durations from the monosodium iodoacetate-injected mice without human umbilical cord mesenchymal stem cell transplantation. Motor performance was expressed as a percentage of the duration on day 0. ***P < 0.001, the control and human umbilical cord mesenchymal stem cell groups versus the monosodium iodoacetate group; #P < 0.05, the control group versus the monosodium iodoacetate group