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(a) Kaplan-Meier survival analysis for progression-free survival 1 (PFS1) after initial crizotinib treatment prior to RECIST-defined progressive disease (PD). The median PFS1 was 9.6 months (95% CI, 5.6-13.6 months). (b) Kaplan-Meier survival analysis for progress-free survival 2 (PFS2) after continuing ALK/ROS1 inhibition with crizotinib beyond PD. The median PFS2 was 5.9 months (95% CI, 0.1-11.7 months). Tick marks represent censored observations.
