Table 3.
Symptoms in patients admitted with hyponatremia
| Findings | Author (Ref.), Year | ||
|---|---|---|---|
| Chow et al. (47),2004 | Arampatzis et al. (49), 2012 | Nigro et al. (48), 2015 | |
| Selection criteria | Serum Na<130 mEq/L Thiazide induced | Serum Na <121 mEq/L ED admission | Serum Na<125 mEq/L 46% admit for sx’s 96% chronic |
| No. of Patients | 223 | 168 | 298 |
| Serum Na mean | 116 mEq/L | 121 mEq/L | 120 mEq/L |
| Serum Na range | 98-128 mEq/L | 97-121 mEq/L | IQR 116-123 mEq/L |
| Confusion | 17% | 20% | 30% |
| Nausea | 38% | 44% | |
| Vomiting | 35% | 30% | |
| Headache | 19% | 27% | |
| Seizures | 0.9% | 16% | 5% |
| In-hospital mortality | 0% | 13% | 5% |
| Fatal cerebral edema | 0% | 0% | 0% |
| osmotic demyelination syndrome (MRI diagnosis) | One casea | 0% | 0% |
Na, sodium; ED, emergency department; sx’s, symptoms; IQR, interquartile range, MRI, magnetic resonance imaging.
a
Serum Na 101 corrected to 116 mEq/L after 36 h, K.M. Chow, personal communication