Table 2.
Nuclear findings of lymphoid cells in thyroid lymphoma, Hashimoto thyroiditis with prominent lymphoid proliferation (HT-PTP), and papillary thyroid carcinoma with prominent lymphocytic infiltration (PTC-PLI) in liquid-based cytology specimens (LBC-S) and conventional specimens (C-S)
| MALT-L (35) | DLBCL (3) | HT-PTP (25) | PTC-PLI (19) | |
|---|---|---|---|---|
| Nuclear size (mean ± SD) | ||||
| LBC-S | 7.7±1.22††† | 8.6±2.43 | 5.8±0.97††† *** | 5.6±1.06††, *** |
| C-S | 5.5±0.59 | 6.5±1.29* | 5.1±0.43** | 4.8±0.30*** |
| Large nuclei (>10%, >10 µm) | ||||
| LBC-S | 62.9% (22)††† | 100% (3) | 4.0% (1)*** | 5.3% (1)*** |
| C-S | 0% (0) | 33.3% (1) | 0% (0) | 0% (0) |
| Swollen naked nuclei | ||||
| LBC-S | 91.4% (32)††† | 100% (3) | 28.0% (7) †, *** | 10.5% (2)*** |
| C-S | 0% (0) | 0% (0) | 0% (0) | 0% (0) |
| Elongated nuclei | ||||
| LBC-S | 85.7% (30)††† | 100% (3) | 20.0% (5)*** | 0% (0)*** |
| C-S | 34.3% (12) | 33.3% (1) | 4.0% (1)** | 0% (0)** |
| Cleaved nuclei | ||||
| LBC-S | 68.6% (24) | 66.7% (2) | 20.0% (5)††† ** | 5.3% (1)** |
| C-S | 85.7% (30) | 100% (3) | 84.0% (21) | 5.3% (1)*** |
MALT-L, mucosa-associated lymphoid tissue lymphoma; DLBCL, diffuse large B-cell cell lymphoma.
*
p < 0.05
**
p < 0.01
***
p < 0.001, vs. MALT-L
†
p < 0.05
††
p < 0.01
†††
p < 0.001, vs. C-S.