Fig. 1.

miR-519d-3p inhibits the malignant phenotype and arrests G1/S phase transition in GC cells. A An RT-qPCR assay was used to test the efficiency of miR-519d-3p mimics and ASO-miR-519d-3p in MGC803 cells. MTT (B) and colony formation assays (C) were performed to test the effect of miR-519d-3p on MGC803 cell proliferation. D The effect of miR-519d-3p on the cell cycle in MGC803 cells was analyzed by flow cytometry. E Transwell invasion assays were conducted in MGC803 cells transfected with miR-519d-3p mimics and ASO-miR-519d-3p, and miR control or ASO control were considered as the corresponding negative controls. * p < 0.05.