Figure 3.

(a) The functional map is overlaid on the MRIcron template brain (ch256). The brain region (yellow cluster) in the mPFC that showed increased memory related brain activation is depicted. The black square indicates the mean position of the MRS voxel, which overlaps with fMRI voxels of the activation cluster. Therefore, this activation cluster served as seed region for the PPI analyses. (b) Concentrations of GABA and GLx before and after the fMRI task are depicted, whereas GABA did not change, Glx concentration increased over time. (c) The Increase in GLx (MRS 2 − MRS 1) correlated positively with memory performance (high confident remembered minus low confident remembered/incorrect) [Color figure can be viewed at http://wileyonlinelibrary.com]