Figure 3.

Hardy–Weinberg equilibrium tests for 2992 tri‐allelic variants on chromosome 7. (a) p‐values of the omnibus exact test vs. variant position. The solid horizontal line corresponds to α = 0.05, and dotted horizontal line corresponds to the Bonferroni‐corrected threshold. Variants colour‐coded according to having excess of heterozygotes (red) or lack of heterozygotes (green) with respect to HWP. (b) QQ‐plot of the omnibus exact p‐values. (c) Observed vs. expected heterozygosity. (d) Omnibus exact p‐values vs. exact p‐values obtained in a test using the females only. Panels b, c and d have variants colour‐coded according to the p‐value of an exact test for EAF (significant to nonsignificant from red to green). Horizontal and vertical lines correspond to α = 0.05