Table 8.
Variant, position (in bp), genotype counts and exact p‐values for six tri‐allelic variants on chromosome 7
| Variant | Position | Males | Females | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AA | AB | AC | BB | BC | CC | AA | AB | AC | BB | BC | CC | ||
| rs36186766 | 1048677 | 12 | 19 | 13 | 7 | 5 | 0 | 8 | 12 | 13 | 8 | 7 | 0 |
| rs111437421 | 5092372 | 38 | 14 | 0 | 2 | 2 | 0 | 32 | 15 | 1 | 0 | 0 | 0 |
| rs217419 | 44563555 | 56 | 0 | 0 | 0 | 0 | 0 | 42 | 4 | 2 | 0 | 0 | 0 |
| rs59542926 | 101495109 | 16 | 39 | 1 | 0 | 0 | 0 | 23 | 22 | 0 | 3 | 0 | 0 |
| rs35141756 | 123671547 | 29 | 19 | 7 | 1 | 0 | 0 | 41 | 5 | 0 | 2 | 0 | 0 |
| rs3863236 | 154655116 | 15 | 17 | 3 | 21 | 0 | 0 | 12 | 24 | 0 | 9 | 3 | 0 |
| Variant | Position | HWP & EAF | HWP (M+F) | HWP (F) | HWP (M) | EAF | |
|---|---|---|---|---|---|---|---|
| rs36186766 | 1048677 | 0.2925 | 0.0337 | 0.1584 | 0.4039 | 0.5200 | |
| rs111437421 | 5092372 | 0.1359 | 0.1532 | 0.6450 | 0.0368 | 0.8837 | |
| rs217419 | 44563555 | 0.0787 | 1.0000 | 1.0000 | 1.0000 | 0.0089 | |
| rs59542926 | 101495109 | 0.0002 | 0.0004 | 0.7260 | 0.0000 | 0.4135 | |
| rs35141756 | 123671547 | 0.0032 | 0.6279 | 0.0397 | 0.4599 | 0.0030 | |
| rs3863236 | 154655116 | 0.0237 | 0.3149 | 0.2352 | 0.0055 | 0.7225 |
HWP & EAF, omnibus exact test for HWP and EAF jointly; HWP (M+F), standard exact test with all individuals; HWP (F), standard exact test for HWP in females; HWP (M) standard exact test for HWP in males; EAF, Fisher exact test for equality of allele frequencies in males and females.