Table 2.
Baseline characteristics of 481 participants in the NEFRONA cohort study according to atherosclerosis progression over the subsequent 2 years
| Characteristic | No (n=192) | Yes (n=289) | P (No versus Yes) |
|---|---|---|---|
| Age, yr | 56 (42–65) | 63 (56–69) | <0.001 |
| Men, N (%) | 109 (57) | 186 (64) | 0.10 |
| Ever smoker, N (%) | 100 (52) | 183 (63) | 0.01 |
| Dyslipidemia, N (%) | 126 (66) | 210 (73) | 0.11 |
| Diabetes mellitus, N (%) | 40 (21) | 97 (34) | 0.002 |
| Hypertension, N (%) | 171 (89) | 271 (94) | 0.04 |
| Systolic BP, mm Hg | 137 (18) | 145 (21) | <0.001 |
| Diastolic BP, mm Hg | 80 (10) | 81 (11) | 0.29 |
| Total cholesterol, mg/dl | 179 (156–202) | 183 (157–213) | 0.31 |
| LDL cholesterol, mg/dl | 102 (85–123) | 105 (86–129) | 0.39 |
| HDL cholesterol, mg/dl | 48 (40–61) | 47 (37–58) | 0.15 |
| Triglycerides, mg/dl | 109 (82–163) | 137 (103–176) | 0.001 |
| Glucose, mg/dl | 95 (86–105) | 102 (91–123) | <0.001 |
| 25-hydroxyvitamin D, ng/ml | 17.2 (11.8–22.3) | 16.2 (11.9–20.7) | 0.54 |
| IMT, mm | 0.72 (0.59–1.01) | 0.92 (0.75–1.14) | <0.001 |
| HsCRP, mg/L | 1.87 (1.02–3.77) | 2.49 (1.23–5.17) | 0.01 |
| CKD stage, N (%) | 0.36 | ||
| 3 | 104 (54) | 139 (48) | |
| 4–5 | 72 (38) | 127(44) | |
| Dialysis | 16 (8) | 23 (8) | |
| Plaque presence at baseline, N (%) | 109 (57) | 226 (78) | <0.001 |
Dyslipidemia: diagnosis of dyslipidemia in the clinical history. Data are median (25th to 75th percentile) for quantitative variables non-normally distributed, mean (SD) for normal variables, and number (percentage) for categorical variables. IMT, average intima-media thickness; HsCRP, high-sensitivity C-reactive protein.