Table 6.
Association between serious fall injuries and kidney transplantation among United States patients ages 18–80 years old initially placed on the waitlist in 2010–2013
| Measure/Modela | Overall | Serious Fall Injurya | |
|---|---|---|---|
| No | Yes | ||
| No. of patients | 37,752 | 35,808 | 1944 |
| No. of patients transplanted | 8924 | 8638 | 286 |
| Total patient-yr | 67,978.9 | 63,020.6 | 4958.3 |
| Transplant rate per 100 patient-yr | 13.1 | 13.7 | 5.8 |
| Hazard ratios for waitlisting by serious fall injury (95% CI) | |||
| Primary analyses | |||
| Crude | 1.00 (Reference) | 0.77 (0.68 to 0.87) | |
| Adjusted, demographicsb | 1.00 (Reference) | 0.73 (0.65 to 0.82) | |
| Adjusted, demographics + clinicalb | 1.00 (Reference) | 0.71 (0.63 to 0.80) | |
| Sensitivity analysesc | |||
| Additional adjustment for | |||
| Dialysis modality | 1.00 (Reference) | 0.71 (0.63 to 0.80) | |
| Peripheral vascular disease | 1.00 (Reference) | 0.71 (0.63 to 0.80) | |
| Amputation | 1.00 (Reference) | 0.71 (0.63 to 0.80) | |
| Inability to walk | 1.00 (Reference) | 0.71 (0.63 to 0.80) | |
| Inability to transfer | 1.00 (Reference) | 0.71 (0.63 to 0.80) | |
| Institutionalization | 1.00 (Reference) | 0.71 (0.63 to 0.80) | |
| Fall injuries with E codes only | 1.00 (Reference) | 0.68 (0.54 to 0.87) | |
| Among those with no fall injuries before waitlisting | 1.00 (Reference) | 0.70 (0.62 to 0.79) | |
| Subgroup analysesc | |||
| Age, yr | |||
| 18–39 | 1.00 (Reference) | 0.62 (0.47 to 0.81) | |
| 40–64 (P40–64×18–39=0.47) | 1.00 (Reference) | 0.74 (0.64 to 0.86) | |
| ≥65 (P≥65×18–39=0.85) | 1.00 (Reference) | 0.68 (0.52 to 0.90) | |
| Sex | |||
| Men | 1.00 (Reference) | 0.68 (0.58 to 0.81) | |
| Women (Pwomen×men=0.61) | 1.00 (Reference) | 0.74 (0.62 to 0.87) | |
| Race/ethnicity | |||
| Non-Hispanic white | 1.00 (Reference) | 0.65 (0.56 to 0.77) | |
| Black (Pblack×white=0.11) | 1.00 (Reference) | 0.80 (0.63 to 1.02) | |
| Hispanic white (PHispanic×white=0.56) | 1.00 (Reference) | 0.78 (0.58 to 1.05) | |
| Other (Pother×white=0.35) | 1.00 (Reference) | 0.83 (0.49 to 1.38) | |
n=37,164 for models. 95% CI, 95% confidence interval.
a
From cohort entry to outcome or censoring.
b
Demographics: age, sex, and race/ethnicity. Clinical: body mass index, dialysis vintage, comorbid diabetes, ischemic heart disease, and hypertension.
c
Using the fully adjusted (demographics + clinical) model.