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Fig. 5. (a) Quenching effect of NIR-II signal at 1530 nm of the NCs/uricase solution under 980 nm excitation after incubation with 1 mM UA or other different analytes. Error bars represent the standard deviations of triplicate experiments. (b) Correlation between NCs-based assay and commercial kit for the detection of UA in 24 human serum samples, which were kindly provided by Fujian Provincial Cancer Hospital, Fuzhou, China. Each data point represents the mean of triplicate experiments.