Table 5. Thermodynamic parameters of the reverse turn modified Pin 1 WW variants. ΔΔG_f is compared across the pseudoallylic strain engineered variants only.

	T M (°C)	ΔGf (kcal mol–1)	ΔΔGf (kcal mol–1)
6	68.7 ± 0.2	1.87 ± 0.04	0
7	72.0 ± 0.4	2.93 ± 0.06	–1.06
8	62.5 ± 0.4	0.97 ± 0.2	0.90
9	74.3 ± 0.3	3.10 ± 0.02	–1.23
10	78.4 ± 0.6	3.45 ± 0.01	–1.58
11	81.8 ± 0.4	3.77 ± 0.01	–1.90
NG	66.9 ± 0.3	1.75 ± 0.2	—