Fig. 1. Operation principles of typical electrochemical SPMs. (a) SECM feedback (FB) mode. (b) SECM substrate generation/tip collection (SG/TC) mode. (c) SECM redox (RC) competition mode. (d) Pt-Based nanoelectrode for non-invasive intracellular recordings. (e) Microbiosensor for specific metabolite detection. (f) Dual electrode SECM tip. (g) SICM for topographic mapping. (h) Nano-FET for specific metabolite detection. (i) SECM-SICM for constant distance mode electrochemical imaging. Please note that all schemes are not true to scale. Species written in brown color code were generated during the analysis for electrochemical detection.
