Fig. 3. (a) Electrochemical (FSCV) and topographic (AC-impedance) imaging of PC12 cells. (b) Cellular uptake of [Ru(NH3)6]3+ as normalized SECM current of single Zea mays root hair cells and cell topography. (c) Electrochemical imaging of glucose uptake by single MCF10A cells using a GOx-based Pt-ME-biosensor. (d) Detection of Chinese hamster ovary (CHO) normal cells (upper panels) and transformed EGFR/CHO cells. The ALP/Ab-EGFR-complex was imaged by the electrochemical detection of PAP. (e) SICM mapping of an AbSc cell to detect surface charge heterogeneities on the cell surface. (f) Potentiometric-SICM mapping of the apparent local conductance to identify paracellular and transcellular pathways of ion transport between Madin-Darby Canine Kidney strain II cells. (a–f) Adapted with permissions from ref. 45, 53, 16, 54, 22 and 55. Copyright 2009, 2012, 2016 and 2017 American Chemical Society.
