Table 3.
CMR indices of diffuse myocardial fibrosis in patients with systemic sclerosis and controls.
| Controls (N = 12) | All SSc (N = 24) | p-value* | SSc without LGE (N = 16) | p-value a | |
|---|---|---|---|---|---|
| ECV (%) | 24.1 ± 3.5 | 30.0 ± 4.2 | < 0.001 | 29.5 ± 4.5 | 0.002 |
| Partition coefficient (λ) | 0.41 ± 0.05 | 0.47 ± 0.05 | < 0.001 | 0.47 ± 0.05 | 0.003 |
| Pre-T1 (ms) | 951 ± 46 | 1005 ± 63 | 0.012 | 998 ± 61 | 0.033 |
| Post-T1 (ms) | 442 ± 27 | 433 ± 57 | 0.608 | 412 ± 44 | 0.048 |
SSc: systemic sclerosis; LGE: late gadolinium enhancement; ECV: extracellular volume fraction; λ: gadolinium partition coefficient; Pre-T1 = pre-contrast T1; Post-T1 = post-contrast T1; CMR: cardiac magnetic resonance.
Values are expressed as mean ± standard deviation.
a
p-values are for comparison to controls.