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Effect of treatment on osteosarcoma lung metastasis PDOX tumor histology. A) Hematoxylin and eosin (H&E)-stained section of the original patient lung metastasis. B) Untreated PDOX tumor. C) PDOX tumor treated with CDDP. D) PDOX tumor treated with rMETase. E) PDOX tumor treated with S. typhimurium A1-R. F) PDOX tumor treated with S. typhimurium A1-R combined with rMETase and G) PDOX tumor treated with S. typhimurium A1-R combined with both rMETase and CDDP. White scale bars: 80µm.
