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Overexpression of NEDD4 increased LATS1 expression. A. Upper panel: Western blotting analysis was used to detect the expression of LATS1 and pAkt in QGY7703 liver cancer cell line after NEDD4 cDNA transfection. Lower panel: Quantitative results are illustrated for panel A. B. Upper panel: The expression of LATS1 and pAkt in SMMC7721 cells were detected by Western blotting after NEDD4 overexpression. Lower Panel: Quantitative results are illustrated for panel B. * P<0.05 vs control.
