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. 2018 Apr 2;17(5):595–604. doi: 10.1080/15384101.2017.1404206

Figure 2.

Figure 2.

ZEB1 inhibition reverses EMT induces by VE-821 and enhances migration ability. (A, B) PANC-1 cells and MGC-803 cells were transiently transfected with Scrambled Control siRNA or ZEB1 siRNA, then added with 5 μM VE-821 for 48 h. Photos of cellular morphology were taken at × 200 magnification. (C) PANC-1 cells and MGC-803 cells were transiently transfected with Scrambled Control siRNA or ZEB1 siRNA, then added with 5 μM VE-821 for 48 h. The expression of ZEB1, E-cadherin and Vimentin was performed by Western Blotting. (D) PANC-1 cells were transiently transfected with Scrambled Control siRNA or ZEB1 siRNA, then added with 5 μM VE-821 for 24 h. Then migration assays were performed and photos of migrated cells were taken at × 200 magnification. **p<0.01 vs. Scrambled Control.