Table 1. Patient characteristics in hospital survivors and non-survivors.
| All patients N = 46 |
Alive n = 19 |
Dead n = 27 |
|
|---|---|---|---|
| Age, yearsa,b | 69 [59–77] | 64 [60–74] | 71[60–80] |
| Sex ratio (male/female) | 2.5 | 2,1 | 2,8 |
| Body mass index, (kg/m2)a,b,c | 25 [22–29] | 25 [21–29] | 25 [23–27] |
| Previous lung diseasea,d | 21 | 7 | 14 |
| COPD | 10 | 3 | 7 |
| Pulmonary cancer | 7 | 2 | 5 |
| Interstitial pneumonia | 5 | 3 | 2 |
| Pulmonary hypertension | 2 | 1 | 1 |
| Asthma | 1 | 1 | 0 |
| SAPS IIa,b | 36 [33–50] | 41 [30–52] | 36 [33–48] |
| SOFAa,b | 4 [3–8] | 4 [3–8] | 4 [3–7] |
| Reason for ICU admissiond | |||
| Acute respiratory failure | 41 | 16 | 25 |
| Sepsis, septic shock | 3 | 2 | 1 |
| Coma | 1 | 1 | 0 |
| Cardiac arrest | 1 | 0 | 1 |
| Days from admission to OLBb | 4 [3–9] | 4 [2–7] | 4 [4–10] |
| SOFAb,e | 8 [4–11] | 7 [4–8] | 11 [4–13] |
| Bilateral infiltrate on CT scand | 42 | 17 | 25 |
| ARDSd | 22 | 8 | 14 |
| OLB in operating roomd | 43 | 19 | 24 |
| Bedside OLBd | 3 | 0 | 3 |
| Systemic corticosteroidsd,e | 12 | 6 | 6 |
| Systemic antibioticsd,e | 29 | 11 | 18 |
| Prophylactic heparind,e | 17 | 4 | 13 |
| Therapeutic heparind,e | 12 | 6 | 6 |
| Hemoglobinb,e | 10 [9–11] | 10 [9–11] | 10 [9–11] |
| Platelet count < 50 G/Ld,e | 3 | 0 | 3 |
| Platelet count 50–150 G/Ld,e | 9 | 3 | 6 |
| Platelet count >150 G/Ld,e | 34 | 18 | 16 |
| Prothrombin time < 3 secd,e | 34 | 17 | 17 |
| Prothrombin time 3–6 secd,e | 12 | 4 | 8 |
| Contributive OLBd | 37 | 16 | 21 |
| ICU length of stayb | 17 [13–25] | 15 [13–25] | 19 [13–25] |
a, on ICU admission.
b, median and interquartile range.
c, 4 missing data because of missing height.
d, number of patients.
e, on the day of OLB.
ARDS, acute respiratory distress syndrome; COPD, chronic obstructive pulmonary disease; CT, computed tomography; ICU, intensive care unit; OLB, open lung biopsy; SAPS II, simplified acute physiology score; SOFA, sequential organ failure assessment score.