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. 2018 May 25;4(5):eaar4418. doi: 10.1126/sciadv.aar4418

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Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

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Fig. 3 — (A) Secondary structure of the 35-bp DNA duplex and the gold label position indicated on the 3′ end of the upper strand. (B) Mapping gold label positions to 3D reconstructions using SAXS data for end-labeled DNA. Left column: Schematic representations of the 10-, 15-, 20-, 25-, 30-, and 35-bp DNA constructs end-labeled with gold nanocrystals used in the study. Middle and right columns: Side (middle) and front (right) views of the 3D reconstructions of the unlabeled samples (shown as gray spheres) and mapped positions of the gold labels (blue to red spheres; blue spheres correspond to the best fit). The placement of the gold labels at the end and off-center is reproduced well.