Table 2.

Menopause and Mood Symptoms at Baseline and 12 Months

		Baseline		12 Months			Between- Group Change over 12 M^a

Mood Symptoms	HIV + (N= 33)	HIV – (N= 33)	P-Value	HIV+ (N=31)	HIV− (N=32)	P-Value	P-Value
Total Center for Epidemiologic Studies Depression Scale	21 (12,29)	10 (5,14)	0.0006^**	19 (10,31)	10 (5,19)	0.005^**	0.89
CESD Score ≥ 16 % (#)	67% (22)	21% (7)	0.0002^**	61% (19)	41% (13)	0.10
Total General Anxiety Disorder-7 Scale	7 (5,15)	2 (1,7)	0.0003^**	9 (5,14)	3 (0,7)	0.001^**	0.89

Menopause Symptoms

Total Menopause Rating Scale (MRS)	15 ± 8	10 ± 7	0.008^**	17 ± 8	11 ± 7	0.002^**	0.59
MRS Item 1: Hot Flash Severity	2 (1,3)	1 (0,3)	0.03^*	2 (1,3)	1 (0,2)	0.09	0.41
Total Hot Flash Related Daily Interference Scale	37 (10,60)	6 (0,20)	0.001^**	36 (19,53)	8 (0,27)	0.001^**	0.99

Data are reported as % (n) for categorical variables. Normally distributed data are reported as mean/SD and non-normally distributed data are presented as median (IQR=interquartile range).

=P<0.05,

^**

=P<0.01.

Represents between-group change (HIV+ vs. HIV−) at 12 months. Within group change for both HIV+ and HIV− women at 12 months was not significant (P= > 0.05) for each variable (MRS, MRS item 1, HFRDIS, GAD-7, and CES-D). Baseline data for the MRS, MRS item 1, and HFRDIS were previously published¹³