Table 2.
Variable | CD34+ | CD34+/CD133+ | CD34+/CXCR4+ | CD34+/VEGF+ | ||||
---|---|---|---|---|---|---|---|---|
% Change (95% CI) | P Value | % Change (95% CI) | P Value | % Change (95% CI) | P Value | % Change (95% CI) | P Value | |
Age (per 10-y increase) | −9.8 (−12.3 to −7.1) | <0.001 | −11.9 (−14.7 to −9.1) | <0.001 | −8.2 (−11.2 to −5.2) | <0.001 | −0.5 (−11.7 to 12.1) | 0.94 |
Body mass index (per 5-U increase) | 6.1 (3.4 to 8.9) | <0.001 | 8 (4.9 to 11.2) | <0.001 | 3.6 (0.5 to 6.7) | 0.02 | −13 (−22 to −3.1) | 0.01 |
GFR (per 10-U increase) | 0.1 (−1.1 to 1.4) | 0.85 | −0.5 (−1.9 to 0.9) | 0.50 | 0 (−1.4 to 1.5) | 0.95 | −6.9 (−11.8 to −1.7) | 0.01 |
Male | 12.2 (5.2 to 19.5) | <0.001 | 9.3 (1.7 to 17.5) | 0.02 | 11.4 (3.5 to 20) | 0.004 | 3.3 (−21.1 to 35) | 0.82 |
Black | −11.7 (−18 to −5) | 0.001 | −9.1 (−16.3 to −1.1) | 0.03 | −6.9 (−14.5 to 1.4) | 0.10 | −15 (−37.7 to 16.1) | 0.31 |
Hypertension | 5.4 (−3.9 to 15.7) | 0.26 | 3.8 (−6.6 to 15.3) | 0.49 | 3.8 (−6.9 to 15.6) | 0.50 | 82.2 (23.1 to 169.9) | 0.003 |
Former or current smoking | 3.8 (−2.5 to 10.4) | 0.24 | 6.3 (−0.9 to 14) | 0.09 | 7.7 (0.2 to 15.7) | 0.04 | −11.6 (−31.9 to 14.9) | 0.36 |
Diabetes mellitus | 2 (−4.2 to 8.7) | 0.54 | 4.5 (−2.7 to 12.2) | 0.23 | 4.1 (−3.2 to 12) | 0.28 | 3.5 (−20.6 to 34.7) | 0.80 |
Hyperlipidemia | 3.7 (−3.9 to 11.9) | 0.35 | 3.8 (−4.8 to 13.1) | 0.40 | 6.2 (−2.8 to 16) | 0.18 | −9.1 (−34 to 25.4) | 0.56 |
Acute myocardial infarction | 19.2 (7.5 to 32.2) | 0.001 | 24.6 (10.7 to 40.2) | <0.001 | 27.8 (13.2 to 44.2) | <0.001 | 141.6 (55.7 to274.3) | <0.001 |
CI indicates confidence interval; CXCR4, chemokine (C-X-C motif) receptor 4; GFR, glomerular filtration rate; and VEGFR, vascular endothelial growth factor receptor.