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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Horm Behav. 2018 Feb 1;101:36–49. doi: 10.1016/j.yhbeh.2018.01.004

Figure 4. Group mean + S.E Fixed Interval (FI) Schedule of Reward in adult mice following developmental exposure to As and PS.

Figure 4

Figure 4

Analysis of FI behavior including Overall rate, pause time, run rate and Inter-response time. Text stated on graphs indicates significance (p ≤ 0.05) main effects. (A) Females showed significant alterations following the As and PS on overall rate, suggesting decreased motivation, with run rate indicating similar deficits. As+PS exposure increased post-reinforcement pause times, while both As and PS increased inter-response times, suggesting additive effects of each exposure (N = 7-10). (B) Analysis of male FI behavior showed significantly enhanced decreases in overall rate and run rate in Pb+PS exposed males, compared to all other treatment groups. As+PS males had increased post-reinforcement pause times and As exposure, and PS marginally, increased inter-response times (N = 8 -12).