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. Author manuscript; available in PMC: 2019 Feb 14.
Published in final edited form as: J Vasc Res. 2018 Feb 14;55(2):87–97. doi: 10.1159/000486571

Fig. 4.

Fig. 4

Exercise training-induced remodeling of rat intramural coronary arterioles: a schematic representation. Wall sections of exercised and sedentary male rat coronary arteriole segments in spontaneous myogenic tone without (a) and with (b, c) inhibitors. a Coronary arterioles in control myogenic tone at 120 mm Hg intraluminal pressure and with the passive diameter. b The effect of the NO inhibitor Nω-nitro-L-arginine (in the presence of prostanoids) reveals an increased (NO-mediated) dilation effect in myogenic tone at 30 mm Hg intraluminal pressure in the coronary arterioles of exercised rats. c The effect of the cyclo-oxygenase inhibitor INDO (in the presence of NO) reveals the presence of endogenous constrictor prostanoids at 120 mm Hg intraluminal pressure in the coronary arterioles of sedentary animals, which is missing in the exercised group.