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. Author manuscript; available in PMC: 2019 May 24.
Published in final edited form as: Chem Commun (Camb). 2018 May 24;54(43):5426–5429. doi: 10.1039/c8cc03097a

Fig. 2. Glucose and LDL induced hIAPP yield intrinsically fluorescent oligomers with increased neurotoxicity.

Fig. 2

(a–d) DIC and (e–h) GFP-filtered fluorescence microscopy images of hIAPP in the absence and presence of glucose and LDL. i b-tc3 cellular toxicity of hIAPP in the presence of 2 μM LDL, 35 mM glucose and 35 mM fructose. j Hemolytic activity of hIAPP in the absence (black) and presence of 2 μM LDL (green), 35 mM glucose (red) and 35 mM fructose (gray).