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. 2018 May 25;8:8138. doi: 10.1038/s41598-018-26456-8

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(A,B) semi-automatic algorithm to track the distance (L) between the left atrioventricular junction and a user-defined point at the mid posterior left atrial (LA) wall on standard CMR 2- and 4-chamber views. (C,D) Longitudinal strain (ε) at any time point (t) in the cardiac cycle from end-diastole (time 0) was calculated as: ε(t) = (L(t) − L₀)/L₀. LA reservoir strain (ε_s), conduit strain (ε_e) and booster strain (ε_a) were calculated at t equals left ventricular end-systole, diastasis and pre-LA systole, respectively, and their corresponding peak strain rates (SR) derived.