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. 2018 May 25;8:8171. doi: 10.1038/s41598-018-25837-3

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The involvement of CD206+ M2-like MΦs in fertilization and implantation. (a) In vitro fertilization rate of oocytes derived from wild type (WT) and CD206 diphtheria toxin receptor (DTR) mice. n; the number of oocytes. (b) The embryo growth rate to blastocyst of fertilized ovum derived from WT and CD206 DTR mice. (c) The photographs of implantation site after embryo transfer derived from WT mice (left panel) and CD206 DTR mice (right panel). (d) The implantation rate of ovum derived from CD206 DTR mice compared to WT mice. n; the number of embryo. N.S; significant compared to WT mice.