Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 May 25;8:8122. doi: 10.1038/s41598-018-26578-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Expression of GFP alone, GFP-Drp1 mutants (K668E corresponding to monomeric Drp1 and G363D corresponding to dimeric Drp1) and GFP-ferritin in HeLa Drp1 KO and in non-modified HeLa (HeLa wt) cell lines. These constructs were used for the calibration of LDVM. The lack of expression of Drp1 in the HeLa Drp1 KO cells resulted in an elongated mitochondrial network compared to the mitochondrial morphology in HeLa wt. Mitochondria are shown in red (transfection with Mito-mNeptune), and the expression of GFP-tagged constructs is shown in green. Scale bar, 10 μm.