Table 1.
Target cell (Cre promoter) | Mean reduction of Ar exon 2 DNA in B cells | P-value | No. of B cells (×106) | P-value | |
---|---|---|---|---|---|
Controls | B-ARKO mice | ||||
B cells (Cd79a) | 93% | <0.0001 | 24 ± 4 | 20 ± 2 | 0.35 |
B cells (Cd19) | 86% | <0.0001 | 20 ± 3 | 20 ± 2 | 0.88 |
Presentation of B cell-specific ARKO model, Cre promoter used, AR knockout level in the model (measured as relative level of Ar exon 2 DNA in the B cell compartment), and total number of CD19+ B cells in spleen in male control and B cell-specific ARKO (B-ARKO) mice. n = 11 and 8 (Cd79a-Cre+ controls and corresponding B-ARKO), n = 10 and 11 (Cd19-Cre+ controls and corresponding B-ARKO). Values represent mean ± s.e.m. P-values from Mann–Whitney test.