Table 2.
Marker | Typical cellular expression | to (Me [IQ25; IQ75]) | t3m (Me [IQ25; IQ75]) | p |
---|---|---|---|---|
MFI-MRP8 | MAC M1 | 2372.33 [1250.74, 2977.14] | 774.4 [695.33, 1032.22] | 0.019 |
MFI CD86 | Activated MO | 783.88 [457.60, 990.84] | 230.17 [178.29, 372.42] | 0.050 |
MFI-CD206 | MAC M2 | 725.00 [409.81, 1038.23] | 1902.2 [905.26, 4212.51] | 0.026 |
MFI-CD163 | MAC M1 | 1653.80 [1400.21, 1885.59] | 1335.6 [718.19, 1439.18] | 0.004 |
TGF/LAP | MAC M2 | 1099.53 [892.44, 1253.50] | 3223 [2407.00, 3560.50] | 0.003 |
Flow cytometry reveals a persistence of MRP(high), CD206(high), CD163(high), TGF/LAP(high) and decreased expression of CD86 3 months after CPB as compared to pre-CPB values