Table 3.
Results of univariate and multivariate analyses of clinicopathological factors affecting the overall survival rate following surgery
| Clinicopathologic variable | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| RR | 95%CI | P value | RR | 95%CI | P value | |
| FOXC2 expression (low/high) | 2.14 | 1.05–4.34 | 0.035a | 2.21 | 1.06–4.57 | 0.033a |
| Age (≤65/> 65) | 1.17 | 0.518–2.66 | 0.70 | – | – | – |
| Gender (male/female) | 1.13 | 0.485–2.62 | 0.78 | – | – | – |
| Liver cirrhosis (negative/positive) | 1.86 | 0.913–3.77 | 0.087 | – | – | – |
| Differentiation (well or moderate/poor) | 1.30 | 0.307–5.49 | 0.72 | – | – | – |
| Pattern of tumor growth (Eg/Ig) | 3.29 | 1.53–7.07 | 0.0023a | 3.06 | 1.37–6.80 | 0.0062a |
| T classification (T1–3/T4) | 4.33 | 1.82–10.34 | < 0.001a | 3.82 | 1.18–12.37 | 0.025a |
| Portal vein invasion (negative/positive) | 2.19 | 1.03–4.65 | 0.042a | 1.31 | 0.477–3.59 | 0.6 |
| AFP level (normal/high) | 1.24 | 0.529–2.91 | 0.62 | – | – | – |
| PIVKA II level (normal/high) | 0.749 | 0.323–1.73 | 0.50 | – | – | – |
RR relative risk, CI confidence interval
aStatistical significance is indicated by P < 0.05