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a. Enrichment of transmitted and non-transmitted rSNV in ASD simplex families. Population significance testing (ASD mutations / Coronary Artery Disease (CAD) mutations) assessing burden of inherited/transmitted variants in high-risk candidate ASD genes relative to coronary artery disease genes. Parents and siblings do are non-ASD. b Enrichment of rSNV in SPD and ASD cohorts. Probability analysis comparing rSNV enrichment in SPD cohort to the ASD population
